Astrocyte lineage cells are essential for functional neuronal differentiation and synapse maturation in human iPSC-derived neural networks

Author:

Klapper Simon D.1,Garg Pretty12,Dagar Sushma1,Lenk Kerstin3,Gottmann Kurt1ORCID,Nieweg Katja12

Affiliation:

1. Institute of Neuro- and Sensory Physiology, Medical Faculty; Heinrich-Heine-University Düsseldorf; Düsseldorf Germany

2. Institute of Pharmacology and Clinical Pharmacy; Phillips-University Marburg; Marburg Germany

3. Faculty of Medicine and Health Technology; Tampere University; Tampere Finland

Funder

Bundesministerium für Bildung und Forschung

Deutsche Forschungsgemeinschaft

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Neurology

Reference49 articles.

1. C-terminal fragment of N-cadherin accelerates synapse destabilization by amyloid-β;Andreyeva;Brain,2012

2. Glial modulation of synaptic transmission in culture;Araque;Glia,2004

3. Glial cells promote dendrite formation and the reception of synaptic input in Purkinje cells from postnatal mice;Buard;Glia,2010

4. Astrocyte differentiation of human pluripotent stem cells: New tools for neurological disorder research;Chandrasekaran;Frontiers in Cellular Neuroscience,2016

5. Thrombospondins are astrocyte-secreted proteins that promote CNS synaptogenesis;Christopherson;Cell,2005

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