Aging restricts the ability of mesenchymal stem cells to promote the generation of oligodendrocytes during remyelination

Author:

Rivera Francisco J.12345ORCID,Fuente Alerie G.5ORCID,Zhao Chao5ORCID,Silva Maria E.12345ORCID,Gonzalez Ginez A.5ORCID,Wodnar Roman34,Feichtner Martina34,Lange Simona34,Errea Oihana5,Priglinger Eleni367ORCID,O'Sullivan Anna348,Romanelli Pasquale48ORCID,Jadasz Janusz J.9ORCID,Brachtl Gabriele1011,Greil Richard10,Tempfer Herbert4712,Traweger Andreas4712ORCID,Bátiz Luis F.213ORCID,Küry Patrick14ORCID,Couillard‐Despres Sebastien478ORCID,Franklin Robin J. M.5ORCID,Aigner Ludwig347ORCID

Affiliation:

1. Laboratory of Stem Cells and Neuroregeneration, Institute of Anatomy, Histology and PathologyFaculty of Medicine, Universidad Austral de Chile Valdivia Chile

2. Center for Interdisciplinary Studies on the Nervous System (CISNe)Universidad Austral de Chile Valdivia Chile

3. Institute of Molecular Regenerative MedicineParacelsus Medical University Salzburg Austria

4. Spinal Cord Injury and Tissue Regeneration Center Salzburg (SCI‐TReCS)Paracelsus Medical University Salzburg Austria

5. Wellcome‐MRC Cambridge Stem Cell Institute & Department of Clinical NeurosciencesUniversity of Cambridge Cambridge UK

6. Ludwig Boltzmann Institute for Experimental and Clinical TraumatologyAUVA Research Center Linz/Vienna Austria

7. Austrian Cluster for Tissue Regeneration Vienna Austria

8. Institute of Experimental NeuroregenerationParacelsus Medical University Salzburg Salzburg Austria

9. Laboratory of Experimental Ophthalmology, Department of OphthalmologyUniversity Hospital Düsseldorf, Heinrich‐Heine‐University Düsseldorf Germany

10. Laboratory for Immunological and Molecular Cancer Research, 3rd Medical Department for Hematology, Medical Oncology, Hemostasiology, Infectious Diseases, and RheumatologyFederal Hospital of Salzburg and Paracelsus Medical University Salzburg Austria

11. Experimental and Clinical Cell Therapy InstituteParacelsus Medical University Salzburg Austria

12. Institute of Tendon and Bone RegenerationParacelsus Medical University Salzburg Austria

13. Centro de Investigación Biomédica (CIB), Facultad de MedicinaUniversidad de los Andes Santiago Chile

14. Department of Neurology, Medical FacultyHeinrich‐Heine‐University Düsseldorf Germany

Funder

Dr. Miriam and Sheldon G. Adelson Medical Research Foundation

Bundesministerium für Bildung und Forschung

Comisión Nacional de Investigación Científica y Tecnológica

Deutsche Forschungsgemeinschaft

Medical Research Council Canada

Wellcome Trust

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Neurology

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