Pathway based analysis of SNPs with relevance to 5-FU therapy: Relation to intratumoral mRNA expression and survival

Author:

Nordgard Silje H.,Alnaes Grethe I.G.,Hihn Björn,Lingjaerde Ole Christian,Liestøl Knut,Tsalenko Anya,Sørlie Therese,Lønning Per Eystein,Børresen-Dale Anne-Lise,Kristensen Vessela N.

Funder

The Norwegian Cancer Society

FUGE Program, NFR

SalusAnsvars Award, Ella

Kristian Nyerrøds Fund

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference51 articles.

1. 5-fluorouracil: mechanisms of action and clinical strategies;Longley;Nat Rev Cancer,2003

2. Disruption of p53 in human cancer cells alters the responses to therapeutic agents;Bunz;JClin Invest,1999

3. Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine, and bile;Heggie;Cancer Res,1987

4. Lethal outcome of a patient with a complete dihydropyrimidine dehydrogenase (DPD) deficiency after administration of 5-fluorouracil: frequency of the common IVS14+1G>A mutation causing DPD deficiency;van Kuilenburg;Clin Cancer Res,2001

5. Heterozygosity for a point mutation in an invariant splice donor site of dihydropyrimidine dehydrogenase and severe 5-fluorouracil related toxicity;van Kuilenburg;Eur J Cancer,1997

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