Candidate biomarkers for the diagnosis and prognosis of drug‐induced liver injury: An international collaborative effort

Author:

Church Rachel J.12,Kullak‐Ublick Gerd A.34,Aubrecht Jiri5,Bonkovsky Herbert L.6,Chalasani Naga7,Fontana Robert J.8,Goepfert Jens C.9,Hackman Frances10,King Nicholas M. P.11,Kirby Simon10,Kirby Patrick12,Marcinak John12,Ormarsdottir Sif13,Schomaker Shelli J.5,Schuppe‐Koistinen Ina14,Wolenski Francis12,Arber Nadir15,Merz Michael316,Sauer John‐Michael11,Andrade Raul J.17,van Bömmel Florian18,Poynard Thierry19,Watkins Paul B.12

Affiliation:

1. Institute for Drug Safety SciencesUniversity of North Carolina at Chapel Hill Research Triangle Park NC

2. Division of Pharmacotherapy and Experimental TherapeuticsUniversity of North Carolina Eshelman School of Pharmacy Chapel Hill NC

3. Department of Clinical Pharmacology and ToxicologyUniversity Hospital Zurich, University of Zurich Switzerland

4. Mechanistic SafetyNovartis Global Drug Development Basel Switzerland

5. Drug Safety R&DPfizer Inc. Groton CT

6. Wake Forest University School of Medicine Winston‐Salem NC

7. School of MedicineIndiana University Indianapolis IN

8. University of Michigan Ann Arbor MI

9. Natural and Medical Sciences Institute Reutlingen Germany

10. Pfizer Inc New York NY

11. Predictive Safety Testing Consortium Tucson AZ

12. Takeda Pharmaceuticals Deerfield IL

13. Global Patient SafetyAstraZeneca R&D Gothenburg Sweden

14. Science for Life Laboratory, Department of Physiology and PharmacologyKarolinska Institute Stockholm Sweden

15. Tel Aviv Sourasky Medical CenterTel Aviv University Israel

16. Discovery and Investigative SafetyNovartis Institutes for Biomedical Research Basel Switzerland

17. Unidad de Gestión Clínica de Aparato Digestivo, Instituto de Investigación Biomédica de Málaga‐IBIMA, Hospital Universitario Virgen de la Victoria, Universidad de MálagaCentro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd) Málaga Spain

18. Section of Hepatology, Clinic of Gastroenterology and HepatologyUniversity Hospital Leipzig Leipzig Germany

19. Department of Hepatology, Groupe Hospitalier Pitié SalpêtrièreUniversity Pierre et Marie Curie, INSERM UMR 938 Paris France

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

Innovative Medicines Initiative

Seventh Framework Programme

European Federation of Pharmaceutical Industries and Associations

University of Nottingham

Publisher

Wiley

Subject

Hepatology

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