The role of human cytochrome P450 2E1 in liver inflammation and fibrosis

Author:

Xu Jun1,Ma Hsiao-Yen1,Liang Shuang1,Sun Mengxi1,Karin Gabriel1,Koyama Yukinori1,Hu Ronglin1,Quehenberger Oswald12,Davidson Nicholas O.3,Dennis Edward A.24,Kisseleva Tatiana5,Brenner David A.1

Affiliation:

1. Department of Medicine; University of California San Diego; La Jolla CA

2. Department of Pharmacology; University of California San Diego; La Jolla CA

3. Department of Medicine; Washington University School of Medicine; St. Louis MO

4. Department of Chemistry and Biochemistry; University of California San Diego; La Jolla CA

5. Department of Surgery; University of California San Diego; La Jolla CA

Funder

National Institutes of Health

Publisher

Wiley

Subject

Hepatology

Reference50 articles.

1. Cytochrome P-4502E1: its physiological and pathological role;Lieber;Physiol Rev,1997

2. CYP2E1: biochemistry, toxicology, regulation and function in ethanol-induced liver injury;Kessova;Curr Mol Med,2003

3. CYP2E1 and oxidative liver injury by alcohol;Lu;Free Radic Biol Med,2008

4. Microsomal generation of reactive oxygen species and their possible role in alcohol hepatotoxicity;Cederbaum;Alcohol Alcohol Suppl,1991

5. Induction of rat hepatic N-nitrosodimethylamine demethylase by acetone is due to protein stabilization;Song;J Biol Chem,1989

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