Comparative potency of obeticholic acid and natural bile acids on FXR in hepatic and intestinal in vitro cell models
Author:
Affiliation:
1. Intercept Pharmaceuticals Inc.; San Diego CA USA
2. Qualyst Transporter Solutions, LLC; Durham NC USA
Funder
Intercept Pharmaceuticals, Inc.
Publisher
Wiley
Subject
General Pharmacology, Toxicology and Pharmaceutics,Neurology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/prp2.368/fullpdf
Reference40 articles.
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4. Effects of feeding bile acids and a bile acid sequestrant on hepatic bile acid composition in mice;Zhang;J Lipid Res,2010
5. Separation of 7 alpha- and 7 beta-hydroxysteroid dehydrogenase activities from clostridium absonum ATCC# 27555 and cellular response of this organism to bile acid inducers;Macdonald;J Lipid Res,1983
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