The androgen-regulated type II serine protease TMPRSS2 is differentially expressed and mislocalized in prostate adenocarcinoma

Author:

Lucas JM,True L,Hawley S,Matsumura M,Morrissey C,Vessella R,Nelson PS

Publisher

Wiley

Subject

Pathology and Forensic Medicine

Reference15 articles.

1. Prostate-localized and androgen-regulated expression of the membrane-bound serine protease TMPRSS2;Lin;Cancer Res,1999

2. Cloning of the TMPRSS2 gene, which encodes a novel serine protease with transmembrane, LDLRA, and SRCR domains and maps to 21q22.3;Paoloni-Giacobino;Genomics,1997

3. Catalytic cleavage of the androgen-regulated TMPRSS2 protease results in its secretion by prostate and prostate cancer epithelia;Afar;Cancer Res,2001

4. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer;Tomlins;Science,2005

5. The membrane-anchored serine protease, TMPRSS2, activates PAR-2 in prostate cancer cells;Wilson;Biochem J,2005

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