Developing functional hydrogels for treatment of oral diseases

Author:

Song Chuanhui1ORCID,Liu Rui1ORCID,Fang Yile1,Gu Hongcheng2,Wang Yu12ORCID

Affiliation:

1. Department of Rheumatology and Immunology Institute of Translational Medicine Nanjing Drum Tower Hospital Affiliated Hospital of Medical School Nanjing University Nanjing China

2. State Key Laboratory of Digital Medical Engineering School of Biological Science and Medical Engineering Southeast University Nanjing China

Abstract

AbstractOral disease is a severe healthcare challenge that diminishes people's quality of life. Functional hydrogels with suitable biodegradability, biocompatibility, and tunable mechanical properties have attracted remarkable interest and have been developed for treating oral diseases. In this review, we present up‐to‐date research on hydrogels for the management of dental caries, endodontics, periapical periodontitis, and periodontitis, depending on the progression of dental diseases. The strategies of hydrogels for treating oral mucosal diseases and salivary gland diseases are then classified. After that, we focus on the application of hydrogels related to tumor therapy and tissue defects. Finally, the review prospects the restrictions and the perspectives on the utilization of hydrogels in oral disease treatment. We believe this review will promote the advancement of more amicable, functional and personalized approaches for oral diseases.

Publisher

Wiley

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