An unusual cause of progressive dyspnoea, pulmonary nodules and pleural effusions

Author:

Venkatesan Sudharsan12ORCID,Ramnani Bharti3,Klebe Sonja24,Mo Lin12

Affiliation:

1. Division of Medicine Royal Darwin Hospital Darwin Northern Territory Australia

2. College of Medicine and Public Health Flinders University Darwin Northern Territory Australia

3. Department of Anatomical Pathology Royal Darwin Hospital Darwin Northern Territory Australia

4. Department of Anatomical Pathology Flinders Medical Centre Adelaide South Australia Australia

Abstract

AbstractEosinophilic granulomatosis with polyangiitis (EGPA) is part of the ANCA‐associated vasculitides, although ANCA‐negative presentations are not infrequent. Asthma, allergic rhinitis and peripheral eosinophilia are classic associations although pleural effusions are an uncommon manifestation of EGPA. We describe a 35‐year old Caucasian adult with asthma who presented with progressive dyspnoea, cough, peripheral eosinophilia and imaging that showed pulmonary nodules with pleural effusions. Biopsy with histopathological review confirmed the diagnosis of EGPA with steroid therapy resulting in significant resolution of symptoms and imaging findings.

Publisher

Wiley

Subject

Pulmonary and Respiratory Medicine

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