Hairy cell leukemia with isolated bone lesions

Author:

Cailly Laura1ORCID,Gruchet Cécile1,Maitre Elsa2,Guidez Stephanie1,Delwail Vincent1,Systchenko Thomas1,Moya Niels1,Sabirou Florence1,Levy Anthony1,Bobin Arthur1,Gardeney Hélène1,Nsiala Laly1,Vonfeld Mathilde1,Chacon Aurélia1,Pichon Aurélien1,Bouyer Sabrina3,Baslé Caroline3,Dindinnaud Elodie3,Chomel Jean‐Claude3,Raimbault Anna3,Borde‐Mougenot Florence4,Troussard Xavier2ORCID,Tomowiak Cécile1ORCID

Affiliation:

1. Department of Hematology and Cellular Therapy, and INSERM CIC1402 CHU La Miletrie, University Hospital Poitiers France

2. Department of Hematology, CHU Cote de Nacre University Hospital Caen France

3. Department of Biology, CHU La Miletrie University Hospital Poitiers France

4. Department of Oncology, CH Saintes Saintes France

Abstract

Key Clinical Message18F‐FDG PET/CT has clinical relevance in HCL at diagnosis and for the follow‐up of patients treated, especially in case of atypical presentations such as bone involvements (which are probably underestimated) and poor bone marrow infiltration.AbstractBone lesions are rarely reported in Hairy Cell Leukemia (HCL). We report two BRAFV600E mutated HCL patients presented bone lesions at foreground, poor bone marrow involvement, and the important role 18F‐FDG PET/CT played in their management. We discuss the crucial role that 18F‐FDG PET/CT could play in HCL routine practice.

Publisher

Wiley

Subject

General Medicine

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