Clinical outcome of <scp>endoscopic‐assisted</scp> transoral surgery for superficial cancer of pharyngo‐esophageal junction-Reference-Cited by-同舟云学术

Clinical outcome of endoscopic‐assisted transoral surgery for superficial cancer of pharyngo‐esophageal junction

Published:2023-06-23 Issue:8 Volume:45 Page:2098-2107
ISSN:1043-3074
Container-title:Head & Neck
language:en
Short-container-title:Head & Neck

Author:

Furue Yasuaki¹²^ORCID,Hori Keisuke¹³,Tomioka Toshifumi⁴^ORCID,Fujii Satoshi⁵⁶,Okano Wataru⁴^ORCID,Shinozaki Takeshi⁴,Kadota Tomohiro¹^ORCID,Yoda Yusuke¹⁷^ORCID,Hayashi Ryuichi⁴,Yano Tomonori¹^ORCID

Affiliation:

1. Department of Gastroenterology and Endoscopy National Cancer Center Hospital East Kashiwa Japan

2. Department of Gastroenterology Kitasato University School of Medicine Sagamihara Japan

3. Department of Gastroenterology Ichinomiyanishi Hospital Ichinomiya Japan

4. Department of Head and Neck Surgery National Cancer Center Hospital East Kashiwa Japan

5. Division of Pathology, Exploratory Oncology Research and Clinical Trial Center National Cancer Center Kashiwa Japan

6. Department of Molecular Pathology Yokohama City University Graduate School of Medicine Yokohama Japan

7. Department of Endoscopy Saitama Cancer Center Kitaadachi Japan

Abstract

AbstractBackgroundEndoscopic‐assisted transoral surgery (TOS) for superficial cancer of the pharyngo‐esophageal junction (PEJ) is risk of stricture, and therapeutic outcomes are unclear. This study aimed to evaluate clinical outcomes of endoscopic‐assisted TOS for superficial PEJ cancers.MethodsWe retrospectively compared clinical outcomes of endoscopic‐assisted TOS for superficial PEJ cancers (group A) and of other sites in the hypopharynx (group B).ResultsThe group A comprised 12 lesions in 12 patients, and group B comprised 198 lesions in 146 patients. Group A and group B exhibited en bloc resection rates of 100% and 99%. Median operative times were 82 and 37 min (p < 0.001). The frequency of stricture and local recurrence in group A was significantly higher in group B (42% vs. 1%, p < 0.001; 25% vs. 6%, p = 0.036). All adverse events could be managed with conservative treatments.ConclusionsEndoscopic‐assisted TOS is not ideal for treating superficial PEJ cancers compared to other sites.

Publisher

Wiley

Subject

Otorhinolaryngology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/hed.27439

Reference25 articles.

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