Optimization of a nonviral transfection system to evaluate Cox-2 controlled interleukin-4 expression for osteoarthritis gene therapyin vitro

Author:

Lang Annemarie1234,Neuhaus Johannes25,Pfeiffenberger Moritz1,Schröder Erik2,Ponomarev Igor5,Weber Yvonne1,Gaber Timo236,Schmidt Michael F. G.1

Affiliation:

1. Institute of Immunology, Department of Veterinary Medicine; Freie Universität Berlin; Germany

2. Department of Rheumatology and Clinical Immunology; Charité University Hospital; Berlin Germany

3. German Rheumatism Research Center; Berlin Germany

4. Berlin-Brandenburg School of Regenerative Therapies; Charité University Hospital; Berlin Germany

5. Research Center of Medical Technology and Biotechnology; Bad Langensalza Germany

6. Berlin- Brandenburg Center of Regenerative Therapies; Charité University Hospital; Berlin Germany

Funder

Federal Ministry for Economic Affairs and Energy

Publisher

Wiley

Subject

Genetics(clinical),Drug Discovery,Genetics,Molecular Biology,Molecular Medicine

Reference60 articles.

1. Osteoarthritis;Goldring;J Cell Physiol,2007

2. Inflammation in osteoarthritis;Goldring;Curr Opin Rheumatol,2011

3. Osteoarthritis or osteoarthrosis: the definition of inflammation becomes a semantic issue in the genomic era of molecular medicine;Attur;Osteoarthritis Cartilage,2002

4. Roles of chondrocytes in the pathogenesis of osteoarthritis;Aigner;Curr Opin Rheumatol,2002

5. The role of cytokines in osteoarthritis pathophysiology;Fernandes;Biorheology,2002

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