Randomized Clinical Trial of First‐Line Genome Sequencing in Pediatric White Matter Disorders

Author:

Vanderver Adeline12ORCID,Bernard Geneviève345,Helman Guy67ORCID,Sherbini Omar1,Boeck Ryan89,Cohn Jeffrey10,Collins Abigail11,Demarest Scott11,Dobbins Katherine12,Emrick Lisa13,Fraser Jamie L.1415,Masser‐Frye Diane16,Hayward Jean17,Karmarkar Swati1819,Keller Stephanie20,Mirrop Samuel21,Mitchell Wendy2223,Pathak Sheel2425,Sherr Elliott26,Haren Keith27,Waters Erica28,Wilson Jenny L.29,Zhorne Leah30,Schiffmann Raphael31,Knaap Marjo S.3233,Pizzino Amy1,Dubbs Holly1,Shults Justine34,Simons Cas67,Taft Ryan J.35,

Affiliation:

1. Division of Neurology Children's Hospital of Philadelphia Philadelphia Pennsylvania USA

2. Perelman School of Medicine University of Pennsylvania Philadelphia Pennsylvania USA

3. Departments of Neurology and Neurosurgery Pediatrics, and Human Genetics, McGill University Montreal Quebec Canada

4. Department of Specialized Medicine, Division of Medical Genetics Montreal Children's Hospital and McGill University Health Centre Montreal Quebec Canada

5. Child Health and Human Development Program Research Institute of the McGill University Health Centre Montreal Quebec Canada

6. Institute for Molecular Bioscience University of Queensland Brisbane Queensland Australia

7. Murdoch Children's Research Institute Royal Children's Hospital Melbourne Victoria Australia

8. Child Neurology Consultants of Austin Austin Texas USA

9. University of Texas at Austin Dell Medical School Austin Texas USA

10. Family Medicine Broadlands Family Practice at Ashburn Ashburn Virginia USA

11. Department of Neurology Anschutz Medical Campus, University of Colorado School of Medicine Aurora Colorado USA

12. Walter Reed National Military Medical Center Bethesda Maryland USA

13. Department of Molecular and Human Genetics Baylor College of Medicine Houston Texas USA

14. Division of Genetics and Metabolism Rare Disease Institute, Children's National Hospital Washington District of Columbia USA

15. George Washington University Washington District of Columbia USA

16. Rady Children's Hospital San Diego California USA

17. Department of Pediatrics Kaiser Oakland Oakland California USA

18. Department of Neurology Le Bonheur Children's Hospital Memphis Tennessee USA

19. Department of Pediatrics University of Tennessee Health Science Center Memphis Tennessee USA

20. Division of Neurology, Department of Pediatrics Emory University Atlanta Georgia USA

21. Pediatric Associates of Austin Austin Texas USA

22. Division of Neurology Children's Hospital of Los Angeles Los Angeles California USA

23. Keck School of Medicine University of Southern California Los Angeles California USA

24. Clinical Neurology Washington University Clinical Associates St Louis Missouri USA

25. Department of Neurology Washington University School of Medicine St Louis Missouri USA

26. Department of Neurology University of California, San Francisco School of Medicine San Francisco California USA

27. Department of Neurology Stanford University Medical Center Stanford California USA

28. Pediatric Associates of Stockton Stockton California USA

29. Division of Pediatric Neurology Oregon Health & Science University School of Medicine Portland Oregon USA

30. Stead Family Department of Pediatrics Carver College of Medicine, University of Iowa Health Care Iowa City Iowa USA

31. Institute of Metabolic Disease Baylor Scott & White Research Institute Dallas Texas USA

32. Department of Child Neurology VU University Medical Center Amsterdam the Netherlands

33. Department of Functional Genomics Amsterdam Neuroscience, VU University Amsterdam the Netherlands

34. Department of Biostatistics University of Pennsylvania Philadelphia Pennsylvania USA

35. Illumina San Diego California USA

Funder

Canadian Institutes of Health Research

Illumina

Publisher

Wiley

Subject

Neurology (clinical),Neurology

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