Pharmacokinetics and Therapeutic Effects of Oltipraz after Consecutive or Intermittent Oral Administration in Rats with Liver Cirrhosis Induced by Dimethylnitrosamine
Author:
Publisher
Elsevier BV
Subject
Pharmaceutical Science
Reference22 articles.
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2. Oltipraz regenerates cirrhotic liver through CCAAT/enhancer binding protein-mediated stellate cell inactivation;Kang;FASEB J,2002
3. Interspecies pharmacokinetic scaling of oltipraz in mice, rats, rabbits, and dogs, and prediction of human pharmacokinetics;Bae;Biopharm Drug Dispos,2005
4. Hepatic and intestinal first-pass effects of oltipraz in rats;Bae;Biopharm Drug Dispos,2005
5. Endotoxin suppresses the oltipraz-mediated induction of major hepatic glutathione transferases and cytochromes P450 in the rat;Maheo;Hepatology,1998
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2. Pharmacokinetic changes of drugs in a rat model of liver cirrhosis induced by dimethylnitrosamine, alone and in combination with diabetes mellitus induced by streptozotocin;Biopharmaceutics & Drug Disposition;2014-08-06
3. Pharmacokinetics of Oltipraz and Its Major Metabolite (RM) in Patients With Liver Fibrosis or Cirrhosis: Relationship With Suppression of Circulating TGF-β1;Clinical Pharmacology & Therapeutics;2010-07-21
4. Stress-Activated Cap'n'collar Transcription Factors in Aging and Human Disease;Science Signaling;2010-03-09
5. Pharmacokinetics of drugs in rats with diabetes mellitus induced by alloxan or streptozocin: comparison with those in patients with type I diabetes mellitus;J PHARM PHARMACOL;2010
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