The use of SHP-2 gene transduced bone marrow mesenchymal stem cells to promote osteogenic differentiation and bone defect repair in rat

Author:

Fan Dapeng1,Liu Shen1,Jiang Shichao2,Li Zhiwei1,Mo Xiumei3,Ruan Hongjiang1,Zou Gang-Ming4,Fan Cunyi1

Affiliation:

1. Department of Orthopaedics; Shanghai Jiaotong University Affiliated Sixth People's Hospital; 600 Yishan Road Shanghai 200233 People's Republic of China

2. Department of Orthopaedics; Shandong Provincial Hospital Affiliated to Shandong University; No.324 Jingwu Road Jinan 250021 Shandong People's Republic of China

3. College of Chemistry, Chemical Engineering and Biotechnology; Donghua University; Shanghai 201620 China

4. Hawaii Gangze Inc; 421 Nahua Street, Suite 146 Honolulu Hawaii 96815

Funder

Nano-tech Foundation of Shanghail

National Natural Science Foundation of China

Publisher

Wiley

Subject

Metals and Alloys,Biomedical Engineering,Biomaterials,Ceramics and Composites

Reference47 articles.

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2. Vascularized bone graft for oncological reconstruction of the extremities: Review of the biological advantages;Muramatsu;Anticancer Res,2014

3. Repair of cranial bone defects with adipose derived stem cells and coral scaffold in a canine model;Cui;Biomaterials,2007

4. Concise review: cell-based strategies in bone tissue engineering and regenerative medicine;Ma;Stem Cells Transl Med,2014

5. The promotion of bone healing by progranulin, a downstream molecule of BMP-2, through interacting with TNF/TNFR signaling;Zhao;Biomaterials,2013

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