Genetically Elevated LDL Associates with Lower Risk of Intracerebral Hemorrhage

Author:

Falcone Guido J.1ORCID,Kirsch Elayna1,Acosta Julian N.1,Noche Rommell B.1,Leasure Audrey1ORCID,Marini Sandro2,Chung Jaeyoon2,Selim Magdy3,Meschia James F.4ORCID,Brown Devin L.5,Worrall Bradford B.6,Tirschwell David L.7,Jagiella Jeremiasz M.8,Schmidt Helena9,Jimenez‐Conde Jordi1011,Fernandez‐Cadenas Israel12,Lindgren Arne1314,Slowik Agnieszka8,Gill Dipender15,Holmes Michael1617,Phuah Chia‐Ling18,Petersen Nils H.1,Matouk, MD Charles N.19,Gunel Murat19,Sansing Lauren20,Bennett Derrick17,Chen Zhengming17,Sun Luan L.21,Clarke Robert1,Walters Robin G.1617,Gill Thomas M.22,Biffi Alessandro2232425ORCID,Kathiresan Sekar22326,Langefeld Carl D.27,Woo Daniel28,Rosand Jonathan2232930,Sheth Kevin N.1,Anderson Christopher D.2232930,

Affiliation:

1. Division of Neurocritical Care & Emergency Neurology, Department of Neurology Yale School of Medicine New Haven CT USA

2. Center for Genomic Medicine Massachusetts General Hospital (MGH) Boston MA USA

3. Department of Neurology Harvard Medical School, Beth Israel Deaconess Medical Center Boston MA USA

4. Department of Neurology Mayo Clinic Jacksonville FL USA

5. Stroke Program, Department of Neurology University of Michigan Health System Ann Arbor MI USA

6. Department of Neurology and Public Health Sciences University of Virginia Health System Charlottesville VA USA

7. Stroke Center, Harborview Medical Center University of Washington Seattle WA USA

8. Department of Neurology Jagiellonian University Medical College Kraków Poland

9. Institute of Molecular Biology and Medical Biochemistry Medical University Graz Graz Austria

10. Neurovascular Research Unit, Department of Neurology Institut Municipal d'Investigacio' Medica‐Hospital del Mar, Universitat Autonoma de Barcelona Barcelona Spain

11. Program in Inflammation and Cardiovascular Disorders, Institut Municipal d'Investigacio' Medica‐Hospital del Mar Universitat Autonoma de Barcelona Barcelona Spain

12. Neurovascular Research Laboratory and Neurovascular Unit Institut de Recerca, Hospital Vall d'Hebron, Universitat Autonoma de Barcelona Barcelona Spain

13. Department of Clinical Sciences Lund, Neurology Lund University Lund Sweden

14. Department of Neurology Skåne University Hospital Lund Sweden

15. Department of Epidemiology and Biostatistics and Department of Stroke Medicine Imperial College London London UK

16. Medical Research Council Population Health Research Unit University of Oxford Oxford UK

17. Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, Medical Research Council Population Health Research Unit University of Oxford Oxford UK

18. Department of Neurology Washington University School of Medicine in St. Louis St. Louis MO USA

19. Department of Neurosurgery Yale School of Medicine New Haven CT USA

20. Division of Vascular Neurology and Stroke, Department of Neurology Yale School of Medicine New Haven CT USA

21. Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care University of Cambridge Cambridge UK

22. Department of Internal Medicine, Geriatric Medicine Yale School of Medicine New Haven CT USA

23. Program in Medical and Population Genetics, Broad Institute Cambridge MA USA

24. Division of Behavioral Neurology, Department of Neurology, MGH Boston MA USA

25. Division of Psychiatry, Department of Psychiatry, MGH Boston MA USA

26. Cardiovascular Disease Prevention Center, MGH Boston MA USA

27. Department of Biostatistical Sciences Wake Forest School of Medicine Winston‐Salem NC USA

28. Department of Neurology University of Cincinnati College of Medicine Cincinnati OH USA

29. Department of Neurology, MGH Boston MA USA

30. Henry and Allison McCance Center for Brain Health, MGH Boston MA USA

Funder

American Heart Association

National Institute of Neurological Disorders and Stroke

National Institute on Aging

Publisher

Wiley

Subject

Neurology (clinical),Neurology

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