Transient distal renal tubular acidosis with nephrogenic diabetes insipidus after general anaesthesia in a dog

Author:

Ku Dayoung1ORCID,Lee Dohee1ORCID,Yun Taesik1ORCID,Koo Yoonhoi1ORCID,Chae Yeon1ORCID,Choi Dongjoon1ORCID,Choi Minseok1ORCID,Kang Byeong‐Teck1ORCID,Yang Mhan‐Pyo1ORCID,Kim Hakhyun1ORCID

Affiliation:

1. Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine Chungbuk National University Cheongju Chungbuk Republic of Korea

Abstract

AbstractA 3‐year‐old, 3.5 kg, female spayed Pomeranian was referred due to persistent vomiting, anorexia, polyuria and polydipsia, 7 days after receiving general anaesthetic for a medial patellar luxation correction. Physical examination revealed lethargy, tachypnoea and 7% dehydration. Complete blood count and serum chemistry results were unremarkable, and venous blood gas analysis revealed hypokalaemia and hyperchloraemic metabolic acidosis with a normal anion gap. Urinalysis revealed a urine specific gravity (USG) of 1.005, pH of 7.0 and proteinuria, and the bacterial culture was negative. Based on these results, the dog was diagnosed with distal renal tubular acidosis, and potassium citrate was prescribed to correct metabolic acidosis. In addition, concurrent diabetes insipidus (DI) was suspected because the dog showed persistent polyuria, polydipsia and a USG below 1.006 despite dehydration. After 3 days of initial treatment, acidosis was corrected, and vomiting resolved. Desmopressin acetate and hydrochlorothiazide were also prescribed for DI, but the USG was not normalized. Based on the insignificant therapeutic response, nephrogenic DI was highly suspected. DI was resolved after 24 days. This case report describes the concomitant presence of RTA and DI in a dog after general anaesthesia.

Publisher

Wiley

Subject

General Veterinary

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