Rituximab as maintenance therapy for patients with follicular lymphoma

Author:

Vidal Liat1,Gafter-Gvili Anat2,Leibovici Leonard2,Shpilberg Ofer3

Affiliation:

1. Beilinson Campus, Rabin Medical Center; Department of Internal Medicine E; 39 Jabotinsky Street Petah-Tiqva Israel 49100

2. Beilinson Campus, Rabin Medical Center; Department of Medicine E; 39 Jabotinsky Street Petah-Tiqva Israel 49100

3. Rabin Medical Center; Institute of Hematology; Petah-Tikva Israel 49100

Publisher

Wiley

Subject

Pharmacology (medical)

Reference58 articles.

1. Maintenance therapy with rituximab leads to a significant prolongation of response duration after salvage therapy with a combination of rituximab, fludarabine, cyclophosphamide, and mitoxantrone (R-FCM) in patients with recurring and refractory follicular and mantle cell lymphomas: Results of a prospective randomized study of the German Low Grade Lymphoma Study Group (GLSG);Forstpointner;Blood,2006

2. Single agent rituximab in patients with follicular or mantle cell lymphoma: clinical and biological factors that are predictive of response and event-free survival as well as the effect of rituximab on the immune system: a study of the Swiss Group for Clinical Cancer Research (SAKK);Ghielmini;Annals of Oncology,2005

3. Prolonged treatment with rituximab in patients with follicular lymphoma significantly increases event-free survival and response duration compared with the standard weekly x 4 schedule;Ghielmini;Blood,2004

4. Maximizing therapeutic benefit of rituximab: maintenance therapy versus re-treatment at progression in patients with indolent non-Hodgkin's lymphoma--a randomized phase II trial of the Minnie Pearl Cancer Research Network;Hainsworth;Journal of Clinical Oncology,2005

5. Hochster HS Weller E Gascoyne RD Ryan TS Habermann TM Gordon LI Maintenance rituximab after CVP results in superior clinical outcome in advanced follicular lymphoma (FL): Results of the E1496 phase III trial from the Eastern Cooperative Oncology Group and the Cancer and Leukemia Group B Blood (ASH Annual Meeting Abstracts) 2005 Abstract 349

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