Levodopa for the treatment of restless legs syndrome

Author:

Scholz Hanna1,Trenkwalder Claudia2,Kohnen Ralf3,Kriston Levente4,Riemann Dieter5,Hornyak Magdolna1

Affiliation:

1. University Medical Center, Freiburg; Interdisciplinary Pain Canter; Breisacher Strasse, 64 Freiburg Germany 79106

2. Paracelsus - Elena Hospital, Centre of Parkinson and Movement Disorders; Klinikstrasse 16 Kassel Germany 34128

3. RPS Research Germany GmbH, Nuremberg and University Erlangen-Nuremberg; Scheurlstrasse 21 Nürnberg Germany 90478

4. University Medical Center, Hamburg - Eppendorf; Department of Medical Psychology; Martinistrasse 52 Hamburg Germany 20246

5. University Medical Center, Freiburg; Department of Psychiatry and Psychotherapy; Hauptstrasse 5 Freiburg Germany 79104

Publisher

Wiley

Subject

Pharmacology (medical)

Reference83 articles.

1. Restless legs syndrome treatment with dopaminergic drugs;Akpinar;Clinical Neuropharmacology,1987

2. Rapid onset of action of levodopa in restless legs syndrome: a double-blind, randomized, multicenter, crossover trial;Benes;Sleep,1999

3. 248.518 A double-blind, randomised, crossover trial investigating the efficacy and safety of the dopamine agonist pramipexole (Sifrol®, 0.25-0.75 mg per day) versus levodopa / benserazide (Madopar® DR, 125-375 mg per day) in patients with restless legs syndrome http://trials.boehringer-ingelheim.com/res/trial/data/pdf/248.518_U08-2249_upload.pdf

4. Comparison of pramipexole (PPX) versus levodopa/benserazide (L/B) in the treatment of restless legs syndrome (RLS): A double blind, randomized, Swiss multi-centre crossover trial;Mathis;Movement Disorders,2006

5. Treatment of restless legs syndrome and periodic movements during sleep with l-dopa: a double-blind, controlled study;Brodeur;Neurology,1988

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