Evaluation of the efficacy and safety of adjuvant treatment to levodopa therapy in Parkinson´s disease patients with motor complications

Author:

Stowe Rebecca1,Ives Natalie1,Clarke Carl E2,Deane Katherine3,van Hilten 4,Wheatley Keith5,Gray Richard6,Handley Kelly1,Furmston Alex1

Affiliation:

1. University of Birmingham; Birmingham Clinical Trials Unit; Edgbaston Birmingham UK B15 2TT

2. College of Medicine and DentalSciences; School of Clinical and Experimental Medicine; University of Birmingham Edgbaston Birmingham West Midlands UK B18 7QH

3. University of East Anglia; Edith Cavell Building; Norwich UK NR4 7TJ

4. Leiden University of Medical Center; Department of Neurology; Albinusdreef 2 Leiden Netherlands 2333 ZA

5. University of Birmingham; Cancer Research UK Clinical Trials Unit, School of Cancer Sciences; Edgbaston Birmingham UK B15 2TT

6. The University of Birmingham; Clinical Trials Unit; Robert Aitken Institute for Clincial Research College of Medical Sciences Birmingham UK B15 2TT

Publisher

Wiley

Subject

Pharmacology (medical)

Reference170 articles.

1. Brooks DJ Kuoppamaki M Vahteristo M Entacapone decreases axial symptoms and tremor in levodopa-treated Parkinson's disease patients experiencing wearing-off symptoms Movement Disorders 2005 S120 (P405)

2. Deuschl G Poewe W Poepping M and the Celomen Study Group Efficacy and safety of entacapone as an adjunct to levodopa treatment in Parkinson's disease (PD): Experience from the Austrian-German six months study Parkinsonism and Related Disorders 1999 S75 (P-TU-100)

3. Poewe W Deuschl G and Celomen Study Group The effect of entacapone in patients with Parkinson's disease (PD): An Austrian-German long-term multicentre study (Celomen Study) European Journal of Neurology 1999 78 (P194)

4. Poewe W Deuschl G Kultalahti E-R Haapaniemi H Leinonen M Reinikainen K Gordin A The efficacy and tolerability of entacapone used in combination with controlled release levodopa preparations in patients with Parkinson's disease Parkinsonism and Related Disorders 2001 S66 (P-TU-221)

5. Efficacy and safety of entacapone in Parkinson's disease patients with suboptimal levodopa response: A 6-month randomized placebo-controlled double-blind study in Germany and Austria (Celomen Study);Poewe;Acta Neurologica Scandinavica,2002

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