1. Randomized trial of intra-arterial recombinant tissue plasminogen activator, intravenous recombinant tissue plasminogen activator and intra-arterial streptokinase in peripheral arterial thrombolysis;Berridge;British Journal of Surgery,1991
2. Prospective randomized trial of high-dose bolus versus low-dose tissue plasminogen activator infusion in the management of acute limb ischaemia;Braithwaite;British Journal of Surgery,1997
3. Phase 2, randomized, open-label study on catheter-directed thrombolysis with plasmin versus rtPA and placebo in acute peripheral arterial occlusion;Comerota;Journal of Drug Assessment,2019
4. A phase 2, randomized, open-label (with blinded plasminogen activator and placebo control groups) study to evaluate the effects of different intra-thrombus infusion regimens of plasmin (human) compared to plasminogen activator and placebo in patients with acute lower extremity native artery or bypass graft occlusion clinicaltrialsregister.eu/ctr-search/trial/2010-019760-36/results
5. A study of intra-thrombus plasmin (human) in acute peripheral arterial occlusion clinicaltrials.gov/ct2/show/NCT01222117