Cell-based therapies for amyotrophic lateral sclerosis/motor neuron disease

Author:

Abdul Wahid S Fadilah1,Law Zhe Kang2,Ismail Nor Azimah1,Lai Nai Ming3

Affiliation:

1. Universiti Kebangsaan Malaysia Medical Centre; Cell Therapy Center; Jalan Yaacob Latif Kuala Lumpur Malaysia 56000

2. Universiti Kebangsaan Malaysia Medical Centre; Department of Medicine, Faculty of Medicine; Kuala Lumpur Malaysia

3. Taylor's University; School of Medicine; Subang Jaya Malaysia

Publisher

Wiley

Subject

Pharmacology (medical)

Reference108 articles.

1. In vivo modulation of neurotrophic and inflammatory factors in the CSF of ALS patients treated with NurOwn (MSC NTF cells).;Aricha;Cytotherapy,2017

2. Modulation of CSF mirnas in ALS phase 2 study participants treated with MSC-NTF cells (NurOwn);Aricha;Neurology,2018

3. Safety and efficacy of transplantation of NurOwn (autologous mesenchymal stromal cells secreting neurotrophic factors) in patients with ALS: a phase 2 randomized double blind placebo controlled trial;Gothelf;Cryotherapy,2017

4. NurOwn phase 2 ALS trial: ALSFRS-R improvement is reflected in subscale domains;Kern;Neurology,2018

5. NCT02017912 A phase 2, randomised, double blind, placebo controlled multicenter study to evaluate safety and efficacy of transplantation of autologous mesenchymal stem cells secreting neurotrophic factors (MSC-NTF) in patients with ALS clinicaltrials.gov/ct2/show/study/NCT02017912

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