Blood pressure lowering efficacy of dual alpha and beta blockers for primary hypertension

Author:

Wong Gavin WK1,Laugerotte Alexandra1,Wright James M1

Affiliation:

1. University of British Columbia; Department of Anesthesiology, Pharmacology and Therapeutics; 2176 Health Sciences Mall Vancouver BC Canada V6T 1Z3

Publisher

Wiley

Subject

Pharmacology (medical)

Reference35 articles.

1. GlaxoSmithKline A multicenter, double-blind, placebo-controlled comparison of Carvedilol (SK&F) 6.25 mg, 12.5 mg, and 25.0 mg administered twice daily in patients with mild and moderate hypertension. http://www.gsk-clinicalstudyregister.com/result_detail.jsp?protocolId=105517%2F021&studyId=80A0B2AA-C084-4ACF-8FA7-23C564527CF2&compound=carvedilol (accessed - day month year)

2. GlaxoSmithKline A multicenter, double-blind, placebo-controlled comparison of carvedilol (SK&F 105517) 6.25mg, 12.5mg, 25mg, and 50mg administered once daily in patients with mild to moderate hypertension. http://www.gsk-clinicalstudyregister.com/result_detail.jsp?protocolId=105517%2F022&studyId=CD325C8A-3EBC-4621-91DE-C403E8D28CFD&compound=carvedilol (accessed day month year )

3. Combined alpha- and beta-adrenoceptor blockade with labetalol in hypertension;Frick;British Medical Journal,1976

4. A double blind trial of labetalol;Kane;British Journal of Clinical Pharmacology,1976

5. Clinical evaluation of labetalol alone and combined with chlorthalidone in essential hypertension: a double blind multicenter controlled study;Lechi;European Journal of Clinical Pharmacology,1982

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