Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain

Author:

Derry Christopher J1,Derry Sheena2,Moore R Andrew3

Affiliation:

1. University of Oxford; Pain Research and Nuffield Department of Clinical Neurosciences (Nuffield Division of Anaesthetics); Pain Research Unit Churchill Hospital Oxford Oxfordshire UK OX3 7LE

2. Oxford Oxfordshire UK

3. Plymouth UK

Publisher

Wiley

Subject

Pharmacology (medical)

Reference64 articles.

1. A randomised, five-parallel-group, placebo-controlled trial comparing the efficacy and tolerability of analgesic combinations including a novel single-tablet combination of ibuprofen/paracetamol for postoperative dental pain;Daniels;Pain,2011

2. A double-blind, parallel-group, placebo controlled randomized, single dose, two center, modified factorial design study comparing the analgesic efficacy of Advil® (400 mg ibuprofen), Tylenol® Extra Strength (1000 mg acetaminophen), the combination of Advil (400 mg ibuprofen) and Tylenol Extra Strength (1000 mg acetaminophen), and the combination of Advil (200 mg ibuprofen) and Tylenol Extra Strength (500 mg acetaminophen) in patients experiencing postoperative dental pain Supplied as full clinical trial report by Reckitt Benckiser

3. Comparison of the analgesic efficacy of concurrent ibuprofen and paracetamol with ibuprofen or paracetamol alone in the management of moderate to severe acute postoperative dental pain in adolescents and adults: a randomized, double-blind, placebo-controlled, parallel-group, single-dose, two-center, modified factorial study;Mehlisch;Clinical Therapeutics,2010

4. A double-blind, parallel-group, placebo-controlled, randomized, single and multiple-dose phase, multi-center factorial design, two-part study examining the analgesic efficacy and tolerability of three fixed-dose combinations of ibuprofen plus acetaminophen (ibuprofen 100 mg plus acetaminophen 250 mg, ibuprofen 200 mg plus acetaminophen 500 mg, ibuprofen 400 mg plus acetaminophen 1000 mg), ibuprofen alone (200 mg and 400 mg), and acetaminophen alone (500 mg and 1000 mg) in adult dental pain following third molar extraction Supplied as full clinical trial report by Reckitt Benckiser

5. A single-tablet fixed-dose combination of racemic ibuprofen/paracetamol in the management of moderate to severe postoperative dental pain in adult and adolescent patients: a multicenter, two-stage, randomized, double-blind, parallel-group, placebo-controlled, factorial study;Mehlisch;Clinical Therapeutics,2010

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