Next-generation sequencing for guiding matched targeted therapies in people with relapsed or metastatic cancer

Author:

Kazmi Farasat1,Shrestha Nipun2,Booth Stephen1,Dodwell David3,Aroldi Francesca1,Foord Thomas4,Nicholson Brian D5,Heesen Philip6,Lord Simon1,Yeoh Kheng-Wei7,Blagden Sarah1

Affiliation:

1. Department of Oncology; University of Oxford; Oxford UK

2. Department of Primary Care and Mental Health; University of Liverpool; Liverpool UK

3. Nuffield Department of Population Health; University of Oxford; Oxford UK

4. University of Oxford; Oxford UK

5. Nuffield Department of Primary Care Health Sciences; University of Oxford; Oxford UK

6. University of Zurich; Zurich Switzerland

7. Radiation Oncology; National Cancer Centre; Singapore Singapore

Publisher

Wiley

Subject

Pharmacology (medical)

Reference50 articles.

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2. Phase I trials as valid therapeutic options for patients with cancer;Adashek;Nature Reviews. Clinical Oncology,2019

3. Alpelisib for PIK3CA-mutated, hormone receptor-positive advanced breast cancer;André;New England Journal of Medicine,2019

4. Randomized phase III trial of concurrent accelerated radiation plus cisplatin with or without Cetuximab for stage III to IV head and neck carcinoma: RTOG (0522);Ang;Journal of Clinical Oncology,2014

5. Emerging agents and new mutations in EGFR-mutant lung cancer;Ayeni;Clinical Cancer Research,2015

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