Guanylate cyclase stimulators for pulmonary hypertension

Author:

Wardle Andrew J1,Seager Matthew J2,Wardle Richard3,Tulloh Robert MR4,Gibbs J Simon R5

Affiliation:

1. Imperial College London; Cardiology, Hammersmith Hospital; Norfolk Place London UK W2 1PG

2. Imperial College London; Academic Section of Vascular Surgery; Charing Cross Hospital Fulham Palace Road London UK W6 8RF

3. Queens Medical Centre; Nottingham UK

4. Bristol Royal Hospital for Children and Bristol Heart Institute; Congenital Heart Disease; Upper Maudlin Street Bristol UK BS2 8BJ

5. Imperial College London; National Heart & Lung Institute; London UK

Publisher

Wiley

Subject

Pharmacology (medical)

Reference108 articles.

1. Riociguat for HF with pulmonary hypertension (PH): Post-hoc analysis of LEPHT by baseline pulmonary vascular resistance (PVR) and pulmonary vascular gradient (PVG);Bonderman;Journal of Cardiac Failure,2014

2. Riociguat for patients with pulmonary hypertension caused by systolic left ventricular dysfunction: a phase IIb double-blind, randomized, placebo-controlled, dose-ranging hemodynamic study;Bonderman;Circulation,2013

3. Bonderman D Ghio S Felix SB Ghofrani HA Michelakis ED Mitrovic V Riociguat improves pulmonary arterial compliance in patients with pulmonary hypertension due to systolic left ventricular dysfunction: Results from a post-hoc analysis of the phase IIB double-blind, randomized, placebo-controlled, dose-ranging hemodynamic LEPHT study American Heart Association Scientific Sessions; 2013 Nov 16-20; Dallas 2013 A17234

4. Left ventricular systolic dysfunction associated with pulmonary hypertension riociguat trial (LEPHT): rationale and design;Ghio;European Journal of Heart Failure,2012

5. Left ventricular systolic dysfunction associated with pulmonary hypertension riociguat trial (LEPHT);Semigran;Circulation,2012

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