First-line therapy for adults with advanced renal cell carcinoma: a systematic review and network meta-analysis

Author:

Aldin Angela1,Besiroglu Burcu1,Adams Anne2,Monsef Ina1,Piechotta Vanessa1,Tomlinson Eve3,Hornbach Carolin1,Dressen Nadine1,Goldkuhle Marius1,Maisch Philipp4,Dahm Philipp5,Heidenreich Axel6,Skoetz Nicole1

Affiliation:

1. Cochrane Haematology, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf; Faculty of Medicine and University Hospital Cologne, University of Cologne; Cologne Germany

2. Institute of Medical Statistics and Computational Biology; Faculty of Medicine and University Hospital Cologne, University of Cologne; Cologne Germany

3. Population Health Sciences, Bristol Medical School; University of Bristol; Bristol UK

4. Department of Urology; University of Ulm; Ulm Germany

5. Urology Section; Minneapolis VA Health Care System; Minneapolis Minnesota USA

6. Department of Urology, Uro-oncology, Special Urological and Robot-assisted Surgery; University Hospital of Cologne; Cologne Germany

Publisher

Wiley

Subject

Pharmacology (medical)

Reference656 articles.

1. Randomized phase II study of sorafenib with or without low-dose IFN in patients with metastatic renal cell carcinoma;Jonasch;Journal of Clinical Oncology. Conference: ASCO Annual Meeting,2007

2. Upfront, randomized, phase 2 trial of sorafenib versus sorafenib and low-dose interferon alfa in patients with advanced renal cell carcinoma: clinical and biomarker analysis;Jonasch;Cancer,2010

3. Atkins MB Hidalgo M Stadler W Logan T Dutcher JP Hudes G A randomized double-blind phase 2 study of intravenous CCI-779 administered weekly to patients with advanced renal cell carcinoma Proceedings of the American Society of Clinical Oncology 2002 10a, Abstract 36

4. Temsirolimus safety profile and management of toxic effects in patients with advanced renal cell carcinoma and poor prognostic features;Bellmunt;Annals of Oncology,2008

5. A phase 3, randomized, 3-arm study of temsirolimus (TEMSR) or interferon-alpha (IFN) or the combination of TEMSR + IFN in the treatment of first-line, poor-risk patients with advanced renal cell carcinoma (adv RCC);Hudes;Journal of Clinical Oncology: ASCO Annual Meeting Proceedings,2006

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