Phenytoin versus valproate monotherapy for partial onset seizures and generalised onset tonic-clonic seizures: an individual participant data review

Author:

Nevitt Sarah J1,Marson Anthony G2,Weston Jennifer2,Tudur Smith Catrin1

Affiliation:

1. University of Liverpool; Department of Biostatistics; Block F, Waterhouse Building 1-5 Brownlow Hill Liverpool UK L69 3GL

2. Institute of Translational Medicine, University of Liverpool; Department of Molecular and Clinical Pharmacology; Clinical Sciences Centre for Research and Education, Lower Lane Fazakerley Liverpool Merseyside UK L9 7LJ

Publisher

Wiley

Subject

Pharmacology (medical)

Reference92 articles.

1. A prospective study between carbamazepine, phenytoin and sodium valproate as monotherapy in previously untreated and recently diagnosed patients with epilepsy;Callaghan;Journal of Neurology, Neurosurgery and Psychiatry,1985

2. Impact of valproate and phenytoin on cognitive function in elderly patients: results of a single-blind randomized comparative study;Craig;Epilepsia,1994

3. Randomised 36-month comparative study of valproic acid, phenytoin, phenobarbital and carbamazepine efficacy in patients with newly diagnosed epilepsy with partial complex seizures;Czapinski;Epilepsia,1997

4. Randomised comparative monotherapy trial of phenobarbitone, phenytoin, carbamazepine, or sodium valproate for newly diagnosed childhood epilepsy;Silva;Lancet,1996

5. Cognitive impairment in new cases of epilepsy randomly assigned to carbamazepine, phenytoin and sodium valproate;Forsythe;Developmental Medicine and Child Neurology,1991

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