Anti-IL-12/23p40 antibodies for induction of remission in Crohn's disease

Author:

MacDonald John K12,Nguyen Tran M1,Khanna Reena2,Timmer Antje3

Affiliation:

1. Robarts Clinical Trials; Cochrane IBD Group; 100 Dundas Street, Suite 200 London ON Canada N6A 5B6

2. University of Western Ontario; Department of Medicine; London ON Canada

3. Carl von Ossietzky University of Oldenburg; Department of Health Services Research; Oldenburg Germany 26111

Publisher

Wiley

Subject

Pharmacology (medical)

Reference78 articles.

1. Pharmacokinetics and exposure-response relationships of ustekinumab during IV induction and SC maintenance treatment of patients with Crohn's disease with ustekinumab: Results from the UNITI-1, UNITI-2, and IM-UNITI studies;Adedokun;Gastroenterology,2016

2. Ustekinumab as induction and maintenance therapy for Crohn's disease;Feagan;New England Journal of Medicine,2016

3. Molecular response to ustekinumab in moderate-to-severe Crohn's disease by serum protein analysis: Results from uniti-1 induction, uniti-2 induction, and imuniti maintenance studies;Li;Gastroenterology,2016

4. A multicenter, double-blind, placebo-controlled phase 3 study of ustekinumab, a human IL-12/23P40 mAB, in moderate to severe Crohn's disease refractory to anti-TFNalpha: UNITI-1;Sandborn;Inflammatory Bowel Diseases,2016

5. Assessment of serum C-reactive protein, fecal lactoferrin, and fecal calprotectin in patients with moderate-severely active Crohns disease: Results from the IM UNITI maintenance study;Sandborn;Gastroenterology,2016

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