Siponimod for multiple sclerosis

Author:

Cao Liujiao12,Li Meixuan3,Yao Liang4,Yan Peijing5,Wang Xiaoqin6,Yang Zhen7,Lao Yongfeng8,Li Huijuan9,Yang Kehu1011,Li Ka12

Affiliation:

1. West China School of Nursing/West China Hospital; Sichuan University; Chengdu China

2. School of Public Health, Evidence-Based Social Science Research Center; Lanzhou University; Lanzhou  China

3. Evidence-Based Medicine Center, School of Basic Medical Sciences; Lanzhou University; Lanzhou China

4. Department of Health Research Methodology, Evidence and Impact; McMaster University; Hamilton Canada

5. Department of Epidemiology and Health Statistics; West China School of Public Health and West China Fourth Hospital, Sichuan University; Chengdu China

6. The Michael G. DeGroote Institute for Pain Research and Care; McMaster University; Hamilton Canada

7. Department of Rheumatology; Tung Wah Group of Hospitals; Hong Kong China

8. The Second Clinical Medical College; Lanzhou University; Lanzhou China

9. School of Public Health, Evidence-Based Social Science Research Center; Lanzhou University; Lanzhou City China

10. Evidence-Based Medicine Center, School of Basic Medical Sciences;  Lanzhou University; Lanzhou China

11. Lanzhou University Institute of Health Data Science; Lanzhou University; Lanzhou China

12. West China School of Nursing /West China Hospital;  Sichuan University; Chengdu China

Publisher

Wiley

Subject

Pharmacology (medical)

Reference90 articles.

1. Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study;Kappos;Lancet,2018

2. Siponimod for patients with relapsing-remitting multiple sclerosis (BOLD): an adaptive, dose-ranging, randomised, phase 2 study;Selmaj;Lancet Neurology,2013

3. Evidence for improved myelination in patients treated with siponimod: Results from the Phase 3 EXPAND MRI Substudy;Arnold;European Journal of Neurology,2020

4. Safety and tolerability of conversion to siponimod in patients with relapsing multiple sclerosis: Interim results of the exchange study;Bar-Or;Multiple Sclerosis Journal,2020

5. Siponimod and Cognition in Secondary Progressive Multiple Sclerosis: EXPAND Secondary Analyses;Benedict;Neurology,2021

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