Poly(ADP-ribose) polymerase (PARP) inhibitors for the treatment of ovarian cancer

Author:

Tattersall Abigail1,Ryan Neil23,Wiggans Alison J4,Rogozińska Ewelina5,Morrison Jo6

Affiliation:

1. Kingston Hospital NHS Foundation Trust; Kingston upon Thames UK

2. The Academic Women’s Health Unit, Translational Health Sciences, Bristol Medical School; University of Bristol; Bristol UK

3. Department of Obstetrics and Gynaecology; St Michael’s Hospital, Bristol, UK; Bristol UK

4. Department of Gynaecological Oncology; Cheltenham General Hospital, Glocestershire Hospitals NHS Foundation Trust; Cheltenham UK

5. The Evidence-Based Medicine Consultancy Ltd; Bath UK

6. Department of Gynaecological Oncology, GRACE Centre; Musgrove Park Hospital, Somerset NHS Foundation Trust; Taunton UK

Publisher

Wiley

Subject

Pharmacology (medical)

Reference306 articles.

1. A study of rucaparib as switch maintenance following platinum-based chemotherapy in patients with platinum-sensitive, high-grade serous or endometrioid epithelial ovarian, primary peritoneal or fallopian tube cancer (ARIEL3) ClinicalTrials.gov website https://clinicaltrials.gov/ct2/show/NCT01968213?term=NCT01968213&rank=1

2. ARIEL3: a phase 3, randomized, double-blind study of rucaparib vs placebo following response to platinum-based chemotherapy for recurrent ovarian cancer (OC);Coleman;Clinical Cancer Research,2018

3. Coleman RL Oza AM Lorusso D Aghajanian C Oaknin A Dean A ARIEL3: a phase 3, randomized, double-blind study of rucaparib vs placebo following response to platinum-based chemotherapy for recurrent ovarian cancer (OC) Clinical Cancer Research 2018 PR06

4. Rucaparib maintenance treatment for recurrent ovarian carcinoma after response to platinum therapy (ARIEL3): a randomised, double-blind, placebo-controlled, phase 3 trial [Erratum appears in Lancet. 2017 Oct 28;390(10106):1948; PMID: 29115226];Coleman;Lancet,2017

5. Rucaparib maintenance treatment for recurrent ovarian carcinoma after response to platinum therapy (ARIEL3): a randomised, double-blind, placebo-controlled, phase 3 trial [Erratum appears in Lancet. 2017 Oct 28;390(10106):1948; PMID: 29115226];Coleman;Lancet (london, England),2017

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