Restrictive versus liberal red blood cell transfusion strategies for people with haematological malignancies treated with intensive chemotherapy or radiotherapy, or both, with or without haematopoietic stem cell support

Author:

Estcourt Lise J1,Malouf Reem2,Trivella Marialena3,Fergusson Dean A4,Hopewell Sally5,Murphy Michael F6

Affiliation:

1. NHS Blood and Transplant; Haematology/Transfusion Medicine; Level 2, John Radcliffe Hospital Headington Oxford UK OX3 9BQ

2. University of Oxford; National Perinatal Epidemiology Unit (NPEU); Old Road Campus Oxford UK OX3 7LF

3. University of Oxford; Centre for Statistics in Medicine; Botnar Research Centre Windmill Road Oxford UK OX3 7LD

4. Ottawa Hospital Research Institute; Clinical Epidemiology Program; 501 Smyth Road Ottawa ON Canada K1H 8L6

5. University of Oxford; Oxford Clinical Trials Research Unit; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences Windmill Road Oxford Oxfordshire UK OX3 7LD

6. Oxford University Hospitals NHS Foundation Trust and University of Oxford; NHS Blood and Transplant; National Institute for Health Research (NIHR) Oxford Biomedical Research Centre; John Radcliffe Hospital Headington Oxford UK

Publisher

Wiley

Subject

Pharmacology (medical)

Reference93 articles.

1. DeZern AE Williams K King K Hand W Levis M Smith BD Liberal vs. restrictive transfusion thresholds in leukemia patients: a feasibility pilot study The American Society of Hematology (ASH) the 57th Annual meeting & exposition Orlando 2015

2. Red blood cell transfusion triggers in acute leukemia: a randomized pilot study;DeZern;Transfusion,2016

3. NCT02086773 Prospective randomized clinical feasibility study of red cell transfusion goals in patients with acute leukemias clinicaltrials.gov/ct2/show/NCT02086773

4. Feasibility of a restrictive red-cell transfusion policy for patients treated with intensive chemotherapy for acute myeloid leukaemia;Jansen;Transfusion Medicine,2004

5. NCT00937053 Maintaining a higher level of haemoglobin: effect on the white cells after bone marrow transplantation in children clinicaltrials.gov/ct2/show/NCT00937053

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