1. University of Liverpool; Department of Biostatistics; Shelley's Cottage Brownlow Street Liverpool UK L69 3GS
2. University of Copenhagen; Department of Mathematics, Faculty of Science; Universitetsparken 5 Copenhagen Ø Denmark 2100
3. Institute of Translational Medicine, University of Liverpool; Department of Molecular and Clinical Pharmacology; Clinical Sciences Centre for Research and Education, Lower Lane Fazakerley Liverpool Merseyside UK L9 7LJ