Xenon as an adjuvant to therapeutic hypothermia in near-term and term newborns with hypoxic-ischaemic encephalopathy

Author:

Rüegger Christoph M12,Davis Peter G234,Cheong Jeanie L234

Affiliation:

1. University Hospital and University of Zürich; Newborn Research, Department of Neonatology; Frauenklinikstrasse 10 Zürich Zürich Switzerland 8091

2. The Royal Women’s Hospital; Newborn Research Centre and Neonatal Services; Melbourne Australia

3. Murdoch Children's Research Institute; Melbourne Australia

4. University of Melbourne; Department of Obstetrics and Gynecology; Melbourne Australia

Publisher

Wiley

Subject

Pharmacology (medical)

Reference54 articles.

1. Moderate hypothermia within 6 h of birth plus inhaled xenon versus moderate hypothermia alone after birth asphyxia (TOBY-Xe): a proof-of-concept, open-label, randomised controlled trial;Azzopardi;Lancet Neurology,2016

2. Anticonvulsant effect of xenon on neonatal asphyxial seizures;Azzopardi;Archives of Disease in Childhood. Fetal and Neonatal Edition,2013

3. NCT01545271 Xenon and cooling therapy in babies at high risk of brain injury following poor condition at birth clinicaltrials.gov/show/NCT01545271

4. NCT02071394 Xenon and cooling therapy in babies at high risk of brain injury following poor condition at birth clinicaltrials.gov/show/NCT02071394

5. Anesthesia and developing brains - implications of the FDA warning;Andropoulos;New England Journal of Medicine,2017

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