1. Bone and Joint Health, Blizard Institute; Queen Mary University of London; London UK
2. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS); University of Oxford; Oxford UK
3. Oxford Clinical Trials Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS); University of Oxford; Oxford UK
4. Department of Trauma and Orthopaedics; The James Cook University Hospital; Middlesbrough UK
5. Barts Health NHS Trust; London UK