Insulin-sensitising drugs versus the combined oral contraceptive pill for hirsutism, acne and risk of diabetes, cardiovascular disease, and endometrial cancer in polycystic ovary syndrome

Author:

Costello Michael F1,Shrestha Bhushan2,Eden John3,Johnson Neil4,Moran Lisa J5

Affiliation:

1. School of Women's & Children's Health, Royal Hospital for Women and IVF Australia; Division of Obstetrics & Gynaecology; Barker Street Randwick Sydney Australia NSW 2031

2. University of New South Wales; School of public health and community medicine; 2/137A Parramatta Road Concord NSW Australia 2137

3. Royal Hospital for Women; Sydney Menopause Centre & Natural Therapies Unit; Locked Bag 2000 Randwick NSW Australia 2031

4. University of Auckland; Department of Obstetrics & Gynaecology; PO Box 92019 Auckland New Zealand 1003

5. Monash University; The Jean Hailes Clinical Research Unit, School of Public Health and Preventive Medicine; Locked bag 29, Monash Medical Centre, Clayton Road Clayton Road Clayton Victoria Australia 3168

Publisher

Wiley

Subject

Pharmacology (medical)

Reference46 articles.

1. The effect of combination therapy with metformin and combined oral contraceptives (COC) versus COC alone on insulin sensitivity, hyperandrogenaemia, SHBG and lipids in PCOS patients;Cibula;Human Reproduction,2005

2. Clinical, endocrine and metabolic effects of metformin added to ethinyl-estradiol-cyproterone acetate in non-obese women with polycystic ovarian syndrome: a randomized controlled study;Elter;Human Reproduction,2002

3. Metformin or antiandrogen in the treatment of hirsutism in polycystic ovary syndrome;Harborne;The Journal of Clinical Endocrinology & Metabolism,2003

4. Endocrine and metabolic effects of metformin versus ethinyl-estradiol-cyproterone acetate in obese women with polycystic ovary syndrome: a randomized study;Morin-Papunen;The Journal of Clinical Endocrinology & Metabolism,2000

5. Metformin versus ethinyl estradiol-cyproterone acetate in the treatment of nonobese women with polycystic ovary syndrome: a randomized study;Morin-Papunen;The Journal of Clinical Endocrinology & Metabolism,2003

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