1. Division of Cancer Sciences; Faculty of Biology, Medicine and Health, The University of Manchester; Manchester UK
2. Division of Population Health, Health Services Research & Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health; The University of Manchester ; Manchester UK
3. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS); University of Oxford; Oxford UK
4. Manchester Academic Health Science Centre; Manchester University NHS Foundation Trust; Manchester UK