Phase 1 trial and pharmacokinetic study of the oral platinum analog satraplatin in children and young adults with refractory solid tumors including brain tumors

Author:

Akshintala Srivandana1,Marcus Leigh12,Warren Katherine E.1,Murphy Robert F.1,Sissung Tristan M.3,Srivastava Anjali3,Goodspeed Wendy J.1,Goodwin Anne1,Brewer Carmen C.4,Zalewski Christopher4,King Kelly A.4,Kim AeRang12,Figg William D.3,Widemann Brigitte C.1

Affiliation:

1. Pediatric Oncology Branch; Center for Cancer Research; National Cancer Institute; National Institutes of Health; Bethesda Maryland

2. Center for Cancer and Blood Disorders; Children's National Medical Center; Washington District of Columbia

3. Clinical Pharmacology Program; Office of the Clinical Director, National Cancer Institute; Bethesda Maryland

4. National Institute on Deafness and Other Communication Disorders; Bethesda Maryland

Publisher

Wiley

Subject

Oncology,Hematology,Pediatrics, Perinatology, and Child Health

Reference31 articles.

1. Satraplatin Investigator's Brochure version 6 2012

2. Satraplatin: An orally available platinum analog for the treatment of cancer;Choy;Expert Rev Anticancer Ther,2006

3. Preclinical antitumor evaluation of bis-acetato-ammine-dichloro-cyclohexylamine platinum(IV): An orally active platinum drug;Kelland;Cancer Res,1993

4. Different accumulation of cisplatin, oxaliplatin and JM216 in sensitive and cisplatin-resistant human cervical tumour cells;Martelli;Biochem Pharmacol,2006

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