Computed tomography‐defined sarcopenia as a risk factor for short‐term postoperative complications in oral cancer patients with free flap reconstruction: A retrospective population‐based cohort study

Author:

Lin Bo123,Lin Jianlin23,Wang Feng123,Wang Yufan123,Shen Shiyue123,Hong Xia123,Yang HuiJun123,Wang Shunji123,Yang Hongyu123ORCID

Affiliation:

1. Department of Oral and Maxillofacial Surgery, Stomatological Center Peking University Shenzhen Hospital Shenzhen Guangdong China

2. Department of Oral and Maxillofacial Surgery Guangdong Provincial High‐Level Clinical Key Specialty Shenzhen Guangdong China

3. Department of Oral and Maxillofacial Surgery Guangdong Province Engineering Research Center of Oral Disease Diagnosis and Treatment Shenzhen Guangdong China

Abstract

AbstractBackgroundPostoperative complications after free flap reconstruction for oral cancer can increase cost and prolong hospitalization. This study explored risk factors for complications, focusing on sarcopenia.MethodsThe study explored the associations between computed tomography‐defined sarcopenia and the occurrence of postoperative complications, adjusted for age, gender, smoking, alcohol, ASA scoring, clinical stage of tumor, tumor site, type of free flap used, presence of tracheotomy, and blood test parameters.ResultsOf 253 patients, 17.39% (44/253) of oral cancer patients had comorbid sarcopenia. Univariate analysis showed an overall postoperative complication rate of 65.90% in the sarcopenia group and 51.67% in the non‐sarcopenia group. Multivariate modeling showed sarcopenia and smoking were major risk factors for total and respiratory complications, increasing the risks by over two‐fold. No factors significantly impacted surgery‐specific complications.ConclusionsThis study identified sarcopenia as a risk factor for postoperative complications in oral cancer patients undergoing flap reconstruction.

Publisher

Wiley

Subject

Otorhinolaryngology

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