Longitudinal Development of Peripapillary Hyper‐Reflective Ovoid Masslike Structures Suggests a Novel Pathological Pathway in Multiple Sclerosis

Author:

Petzold Axel1234ORCID,Coric Danko15,Balk Lisanne J.15,Hamann Steffen6,Uitdehaag Bernard M. J.5,Denniston Alastair K.478,Keane Pearse A.6,Crabb David P.9ORCID

Affiliation:

1. Dutch Expertise Center for Neuro‐Ophthalmology and Multiple Sclerosis Center, Departments of Neurology and Ophthalmology Amsterdam University Medical Center Amsterdam The Netherlands

2. Moorfields Eye Hospital and National Hospital for Neurology and Neurosurgery London United Kingdom

3. University College London Queen Square Institute of Neurology London United Kingdom

4. National Institute for Health Research Biomedical Research Centre at Moorfields Eye Hospital and University College London Institute of Ophthalmology London United Kingdom

5. Multiple Sclerosis Center and Department of Neurology Amsterdam University Medical Center Amsterdam The Netherlands

6. Department of Ophthalmology, Rigshospitalet University of Copenhagen Copenhagen Denmark

7. Department of Ophthalmology University Hospitals Birmingham National Health Service Foundation Trust Birmingham United Kingdom

8. Academic Unit of Ophthalmology Institute of Inflammation and Ageing, University of Birmingham Birmingham United Kingdom

9. Optometry and Visual Sciences City, University of London London United Kingdom

Funder

National Institute for Health Research

Stichting MS Research

Publisher

Wiley

Subject

Neurology (clinical),Neurology

Reference55 articles.

1. Über Complication von Sehnervenentzündung mit Gehirnkrankheiten;Graefe A;Arch Ophthalmol,1860

2. On cases of retro‐ocular neuritis;Nettleship E;Trans Ophthalmol Soc UK,1884

3. Cases of optic neuritis;Norris W;Trans Am Ophthalmol Soc,1874

4. Optical coherence tomography in multiple sclerosis: a systematic review and meta-analysis

5. The Optic Disc Drusen Studies Consortium Recommendations for Diagnosis of Optic Disc Drusen Using Optical Coherence Tomography

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