Quantitative method for analysis of tobacco-specific N -nitrosamines in mainstream cigarette smoke by using heart-cutting two-dimensional liquid chromatography with tandem mass spectrometry

Author:

Chen Min12,Wang Leijun2,Dong Huizhong2,Shao Xi1,Wu Da2,Liu Baizhan2,Zhang Xiangmin1,Chen Chaoying2

Affiliation:

1. Department of Chemistry; Fudan University; Shanghai P. R. China

2. Technology Center, Shanghai Tobacco Group Co., Ltd.; Shanghai P. R. China

Publisher

Wiley

Subject

Filtration and Separation,Analytical Chemistry

Reference30 articles.

1. N’-Nitroso-nornicotine in tobacco;Hoffmann;Science,1974

2. Biochemistry, biology, and carcinogenicity of tobacco-specific N-nitrosamines;Hecht;Chem. Res. Toxicol.,1998

3. Increased expression of cyclooxygenase in rat lung tumors induce by the tobacco-specific nitrosamine 4-(Methylnitrosamine)-4-(3-pyridyl)-1-buta-none: The impact of a high - fat diet;Ei-bayouny;Cancer Res.,1999

4. Quantitative proteomic analysis revealed 4-(methylnitrosamino)-1-(3-pyridinyl)-1-butanone-induced up-regulation of 20S proteasome in cultured human fibroblast cells;Prins;J. Proteome Res.,2012

5. Determination of N-nitrosodimethylamine in the smoke of high-nitrate tobacco cigarettes;Morie;Beitr. Tabak. Int.,1973

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