Targeted and nontargeted screening and identification of 50 antihypertensive adulterants in dietary supplements and herbal medicines using quadrupole–orbitrap high resolution mass spectrometry with compound database

Author:

Guo Changchuan123,Niu Chong123,Zhou Liming4,Wang Wenxin123,Nie Yanjun123,Liu Qi123,Zhang Lei123,Chen Zhen123,Wang Weijian123,Xu Yuwen123ORCID

Affiliation:

1. Chemical Drug DivisionShandong Institute for Food and Drug Control Jinan Shandong P. R. China

2. Shandong Research Center of Engineering and Technology for Consistency Evaluation of Generic Drugs Jinan Shandong P. R. China

3. NMPA Key Laboratory for Research and Evaluation of Generic Drugs Jinan Shandong P. R. China

4. Drug Evaluation DivisionShandong Center for Food and Drug Evaluation and Certification Jinan Shandong P. R. China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Filtration and Separation,Analytical Chemistry

Reference19 articles.

1. National Medical Product Administration.National Medical Product Administration Supplementary Test Method 2009032.

2. Study on the rapid detection method for the illegal addition of chemical components in antihypertensive health products and Chinese Patent Medicines.;Liu J. J.;Chin. Tradit. Pat. Med.,2008

3. Rapid detection of four antihypertensive chemicals adulterated in Traditional Chinese Medicine for hypertension using TLC‐SERS.;Zhu Q. X.;Spectrosc. Spect. Anal.,2014

4. Rapid detection of three chemical components added illegally into antihypertensive health food by TLC concentration in situ combined with micro‐raman spectroscopy method.;Xu F.;Chem. J. Chin. Univ,2018

5. Study on the method for separation and identification of 9 antihypertensives by HPLC.;Liu J. J.;Chin. J. Mod. Appl. Pharm.,2008

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