Development of an automated dual‐mode supercritical fluid chromatography and reversed‐phase liquid chromatography mass‐directed purification system for small‐molecule drug discovery
Author:
Affiliation:
1. Department of Medicinal ChemistryTheravance, Inc South San Francisco CA USA
Publisher
Wiley
Subject
Filtration and Separation,Analytical Chemistry
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/jssc.201301366
Reference31 articles.
1. High-Throughput Mass-Directed Parallel Purification Incorporating a Multiplexed Single Quadrupole Mass Spectrometer
2. High throughput HPLC/MS purification in support of drug discovery
3. High-throughput preparative process utilizing three complementary chromatographic purification technologies
4. Comparison of Preparative HPLC/MS and Preparative SFC Techniques for the High-Throughput Purification of Compound Libraries
5. Comparison of LC/MS and SFC/MS for Screening of a Large and Diverse Library of Pharmaceutically Relevant Compounds
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