Determination of then-octanol/water partition coefficients of weakly ionizable basic compounds by reversed-phase high-performance liquid chromatography with neutral model compounds-Reference-Cited by-同舟云学术

Determination of then-octanol/water partition coefficients of weakly ionizable basic compounds by reversed-phase high-performance liquid chromatography with neutral model compounds

Published:2014-10-13 Issue:22 Volume:37 Page:3226-3234
ISSN:1615-9306
Container-title:Journal of Separation Science
language:en
Short-container-title:J. Sep. Science

Author:

Liang Chao¹,Han Shu-ying¹²,Qiao Jun-qin¹,Lian Hong-zhen¹,Ge Xin¹

Affiliation:

1. State Key Laboratory of Analytical Chemistry for Life Science; School of Chemistry and Chemical Engineering and Center of Materials Analysis; Nanjing University; Nanjing China

2. College of Pharmacy; Nanjing University of Chinese Medicine; Nanjing China

Funder

National Natural Science Foundation of China

National Basic Research Program of China

Publisher

Wiley

Subject

Filtration and Separation,Analytical Chemistry

Reference40 articles.

1. Property-Based Design: Optimization of Drug Absorption and Pharmacokinetics

2. Partition coefficients and their uses

3. OECD n 1989

4. OECD n 1981

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