Study of the in vitro metabolism of TJ0711 using ultra high performance liquid chromatography with quadrupole time-of-flight and ultra fast liquid chromatography with quadrupole linear ion trap mass spectrometry
Author:
Affiliation:
1. Department of pharmaceutics; School of pharmacy, Tongji medical college
2. Hubei Engineering Research Center for Novel Drug Delivery Systems; Huazhong University of Science and Technology; Wuhan China
Funder
Ministry of Science & Technology of China
Publisher
Wiley
Subject
Filtration and Separation,Analytical Chemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/jssc.201500068/fullpdf
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1. Pharmacological effects of an aldehyde type α/β-adrenoceptor blocking agent with vasodilating properties
2. Synthesis and adrenolytic activity of 1-(1H-indol-4-yloxy)-3-(2-(2-methoxy phenoxy)ethylamino)propan-2-ol analogs and its enantiomers. Part 2
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1. Simultaneous Quantitation of a Novel α1/β1-Blocker TJ0711 and Its Two Metabolites in Dog Plasma Using LC-MS/MS and Its Application to a Pharmacokinetic Study after Intravenous Infusion;Pharmaceutics;2019-01-18
2. Accurate determination of a novel vasodilatory β -blocker TJ0711 using LC-MS/MS: Resolution of an isobaric metabolite interference in dog plasma;Biomedical Chromatography;2018-02-12
3. Enantioselective determination of 1-[4-(2-methoxyethyl)phenoxy]-3-[2-(2-methoxyphenoxy)ethylamino]-2-propanol hydrochloride, a novel antihypertensive agent, in rat plasma and tissues by liquid chromatography-tandem mass spectrometry;Journal of Separation Science;2017-09-26
4. Screening and Identification of the Metabolites in Rat Plasma and Urine after Oral Administration of Areca catechu L. Nut Extract by Ultra-High-Pressure Liquid Chromatography Coupled with Linear Ion Trap–Orbitrap Tandem Mass Spectrometry;Molecules;2017-06-21
5. Characterization of an epoxide-derived metabolite of dictamnine using high-performance liquid chromatography with hybrid linear trap quadrupole orbitrap mass spectrometry;Journal of Separation Science;2016-11-25
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