Determination of rabeprazole enantiomers in dog plasma by supercritical fluid chromatography tandem mass spectrometry and its application to a pharmacokinetic study

Author:

Su Chong1,Yang Hong1,Meng Xiangjun1,Fawcett J. Paul2,Cao Jianming3,Yang Yan1,Gu Jingkai14

Affiliation:

1. College of Life Science Jilin University Changchun P. R. China

2. School of Pharmacy University of Otago Dunedin New Zealand

3. Department of Technology Waters Corporation Shanghai China

4. Clinical Pharmacology Center Research Institute of Translational Medicine The First Hospital of Jilin University Changchun P. R. China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Filtration and Separation,Analytical Chemistry

Reference22 articles.

1. Rabeprazole

2. Pharmacogenetics of the Proton Pump Inhibitors: A Systematic Review

3. Prescribing information of ACIPHEX® (rabeprazole sodium) delayed release tablets. Eisai Co. Ltd. Tokyo Japan.2008. Available from:http://www.accessdata.fda.gov/drugsatfda_docs/label/2008/020973s022lbl.pdf.

4. Cytochrome P450 and the metabolism of proton pump inhibitors – emphasis on rabeprazole;Ishizaki T.;Aliment Pharmacol. Ther,1999

5. Enantioselective disposition of rabeprazole in relation to CYP2C19 genotypes

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