Influence of protein properties and protein modification on biodistribution and tumor uptake of anticancer antibodies, antibody derivatives, and non-Ig scaffolds

Author:

Warnders Frank-Jan1ORCID,Lub-de Hooge Marjolijn N.12,de Vries Elisabeth G. E.3,Kosterink Jos G. W.14ORCID

Affiliation:

1. Department of Clinical Pharmacy and Pharmacology; University Medical Center Groningen, University of Groningen; Groningen The Netherlands

2. Department of Nuclear Medicine and Molecular Imaging; University Medical Center Groningen, University of Groningen; Groningen The Netherlands

3. Department of Medical Oncology; University Medical Center Groningen, University of Groningen; Groningen The Netherlands

4. PharmacoTherapy, Epidemiology & Economy; Groningen Research Institute of Pharmacy, University of Groningen; Groningen The Netherlands

Publisher

Wiley

Subject

Drug Discovery,Pharmacology,Molecular Medicine

Reference222 articles.

1. Reichert JM Therapeutic monoclonal antibodies approved or in review in the EU or the US http://www.antibodysociety.org/news/approved-antibodies 2018

2. Next generation antibody drugs: pursuit of the “high-hanging fruit;Carter;Nat Rev Drug Discov,2018

3. Non-immunoglobulin scaffolds: A focus on their targets;Skrlec;Trends Biotechnol,2015

4. Antibody positron emission tomography imaging in anticancer drug development;Lamberts;J Clin Oncol,2015

5. 89Zr-bevacizumab PET imaging in primary breast cancer;Gaykema;J Nucl Med,2013

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