Brief Report: A Phase II b Trial of a Novel Extended‐Release Microsphere Formulation of Triamcinolone Acetonide for Intraarticular Injection in Knee Osteoarthritis

Author:

Conaghan Philip G.1,Cohen Stanley B.2,Berenbaum Francis3,Lufkin Joelle4,Johnson James R.4,Bodick Neil4

Affiliation:

1. University of Leeds and NIHR Leeds Biomedical Research Centre Leeds UK

2. University of Texas Southwestern Medical School Dallas

3. Pierre and Marie Curie University Paris France

4. Flexion Therapeutics Burlington Massachusetts

Funder

Flexion Therapeutics

NIHR Leeds Biomedical Research Centre

Publisher

Wiley

Subject

Immunology,Rheumatology,Immunology and Allergy

Reference15 articles.

1. Clinical aspects, pathology and pathophysiology of osteoarthritis;Goldring SR;J Musculoskelet Neuronal Interact,2006

2. OARSI guidelines for the non-surgical management of knee osteoarthritis

3. Intra-articular Corticosteroids for Osteoarthritis of the Knee

4. Synovial and systemic pharmacokinetics of triamcinolone acetonide following intra‐articular injection of an extended‐release microsphere‐based formulation (FX006) or standard crystalline suspension in patients with knee osteoarthritis;Kraus VB;Osteoarthritis Cartilage,2017

5. An Intra-Articular, Extended-Release Formulation of Triamcinolone Acetonide Prolongs and Amplifies Analgesic Effect in Patients with Osteoarthritis of the Knee

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