Affiliation:
1. Department of Applied Chemistry Waseda University 513 Wasedatsurumakicho Shinjuku Tokyo 162-0041 Japan
Abstract
AbstractFluorine‐containing molecules have attracted much attention in medicinal, agrochemical, and materials sciences because they offer unique physical and biological properties. Therefore, many efficient fluorination reactions have been developed over the years. Recent advancements in fluorination chemistry have expanded the range of substrates, and regioselectivity/stereoselectivity control has also been achieved. Ring‐opening fluorination is an efficient method to construct complex fluorine‐containing molecules with diversity, starting from simple cyclic compounds. This review aims to summarize developments in ring‐opening fluorination, particularly with larger‐sized cyclic compounds. Fluorine introduction and bond cleavage of cyclic compounds such as carbocycles, heterocycles, and aromatics provide efficient access to fluorine‐containing compounds that are difficult to be synthesized by conventional methods.
Subject
Materials Chemistry,General Chemical Engineering,Biochemistry,General Chemistry
Cited by
6 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献