DIEP flap perfusion assessment using microdialysis versus Doppler ultrasonography: A comparative study

Author:

Sorotos Michail1,Firmani Guido1ORCID,Tornambene Roberta2,Marrella Domenico2ORCID,Paolini Guido1,Santanelli di Pompeo Fabio13ORCID

Affiliation:

1. Faculty of Medicine and Psychology Sapienza University of Rome – Sant'Andrea Hospital Rome Italy

2. Department of Human Pathology, Division and Residency Program in Plastic, Reconstructive and Aesthetic Surgery University of Messina Messina Italy

3. Chair of Plastic Surgery, Faculty of Medicine and Psychology Sapienza University of Rome – Sant'Andrea Hospital Rome Italy

Abstract

AbstractBackgroundThe increasing number of buried free‐tissue transfer procedures and the need for an objective method to evaluate vascular complications of free flaps has led to the development of new technologies. Microdialysis has been used to monitor free flaps using interstitial biological markers. Previous uses mainly focused on muscular flaps. Our aim is to compare external Doppler ultrasonography (EDU) evaluation versus microdialysis in the early follow‐up of adipocutaneous flaps, and propose an efficient postoperative monitoring protocol.MethodsWe retrospectively assessed 68 consecutive DIEP flaps (50 patients) performed between January 2019 and March 2021. All flaps received standardized post‐operative monitoring using clinical signs, EDU and microdialysis. Glucose and lactate concentrations were assessed using glucose <1 mmol/L and lactate >6 mmol/L as ischemic trend thresholds. We calculated Glucose/Lactate ratio as a new parameter for the assessment of flap viability.ResultsAmong all the 68 flaps, two flaps returned to the operative theater when a combination of unsatisfactory microdialysis values and clinical/EDU signs identified vascular impairment; only one developed total flap necrosis. Reoperation rate was 2.94% with an overall flap success rate of 98.53%. External Doppler ultrasonography had 100% sensitivity and 82% specificity, while microdialysis had 100% sensitivity and 100% specificity.ConclusionsMicrodialysis values proved flap viability sooner than external Doppler ultrasonography, making it an excellent tool for post‐operative monitoring. With the appropriate thresholds for glucose and lactate concentrations, and glucose/lactate ratio used as a new parameter, it can help potentially avoiding unnecessary re‐explorations, and reducing flap ischemia times.

Publisher

Wiley

Subject

Surgery

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